Kawm paub ntau ntxiv txog Kev Txiav Txim Siab Drosophila! Txhim kho koj cov kev tshawb fawb nrog Biologix Drosophila cov khoom!

Thaum lipid biologist Usha Acharya ntawm National Cancer Institute (NCI) tinkered nrog lipid tawg txoj hauv kev hauv Drosophila melanogaster, nws pom ib yam dab tsi txaus ntshai. Thaiv cov tshuaj tiv thaiv biochemical coj mus rau lipid molecule accumulating mus rau theem siab txaus los ua kom muaj kev ntxhov siab hauv cov yoov. Txawm li cas los xij, cov kab muaj sia nyob.

Thaum tshawb nrhiav yuav ua li cas yoov yoog raws li cov xwm txheej no, Acharya pom muaj qib ntawm cov enzyme-CG8093- hauv lawv lub siab. Tam sim no, nws pab neeg tau txheeb xyuas tias cov lipase yog synthesized hauv plab ntawm Drosophila. Hauv kev teb rau cov zaub mov muaj roj, nws tawm ntawm lub plab mus rau lub hlwb kom cuam tshuam rau kev tsim cov tshuaj insulin. Cov txiaj ntsig, luam tawm hauv Nature Communications, piav qhia txog kev sib txuas molecular ntawm kev noj zaub mov muaj roj thiab insulin secretion hauv hlwb.

Txhawm rau tshawb xyuas CG8093, Usha Acharya pab pawg tau tsim cov kab ya ya uas qhia txog ntsuab fluorescent protein-tagged version ntawm cov molecule hauv plab. Siv fluorescence microscopy, lawv tau taug qab lub glowing molecule tag nrho txoj kev mus rau lub hlwb, qhov chaw uas nws tau nthuav tawm ntau nyob rau hauv lub pars intercerebralis, ib cheeb tsam uas muaj cov insulin-tsim hlwb. Thaum cov kws tshawb fawb soj ntsuam cov noob qhia cov duab qhia chaw ntawm CG8093, lawv tau pom cov qib tsis txaus ntseeg hauv lub hlwb thiab lub paj hlwb hauv nruab nrab piv rau lub plab, tawm tswv yim tias CG8093 tau ua ke hauv plab ua ntej txav mus rau hauv lub hlwb. Kev lig kev cai ntawm naming Drosophila noob tom qab lawv lub luag hauj lwm tshwm sim Usha Acharya hu rau lub enzyme Vaha.

Thaum kawg, pab pawg tshawb fawb xav ua kom lawv cov kev sim ua rau hauv organoids los sim rau kev sib tham hauv nruab nrog cev, Usha Acharya hais. "Tab sis qhov ntawd yuav siv sij hawm peb."

Kev tshawb fawb ntawm drosophila thwmsim tsis tuaj yeem sib cais los ntawm ntau yam khoom siv drosophila thiab cov cuab yeej siv. Biologix cov khoom muag kub muag, cov tshuaj drosophila series thiab stereo microscopes, tau hlub los ntawm ntau tus kws tshawb fawb drosophila. Nws muaj xws li: drosophila vials, fwj, kaw, thiab lwm yam.

Higher-Quality thiab ntau logical nqi! Txhim kho koj cov kev sim drosophila nrog Biologix!

Nqe lus hais los ntawm The Scientist